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12 papers reviewed

Thermal Therapy — Sauna, Infrared & Cold Exposure for Fertility

2013 · prospective · 1 of 12

Seminal and molecular evidence that sauna exposure affects human spermatogenesis

Garolla A, Torino M, Sartini B, et al. · Human Reproduction

Finnish sauna (80-90C, 15 min, 2x/week for 3 months) significantly reduced sperm concentration, motility, and mitochondrial membrane potential. Chromatin and DNA integrity also impaired. All parameters recovered 6 months after stopping.

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2007 · cohort · 2 of 12

Wet heat exposure: a potentially reversible cause of low semen quality in infertile men

Shefi S, Tarapore PE, Walsh TJ, et al. · International Brazilian Journal of Urology

Infertile men who discontinued hot tub/hot bath use showed a mean 491% increase in total motile sperm count within 3-6 months. About half of subjects had clinically significant improvement. Heat avoidance is a first-line male fertility intervention.

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1984 · experimental · 3 of 12

The effect of a single sauna exposure on spermatozoa

Brown-Woodman PD, Post EJ, Brindle GC, et al. · Archives of Andrology

A single sauna session did not significantly alter sperm count, motility, or morphology. Suggests acute occasional exposure is lower risk than repeated use.

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1986 · experimental · 4 of 12

Endocrine effects of repeated sauna bathing

Kukkonen-Harjula K, Kauppinen K · Acta Physiologica Scandinavica

Seven women exposed to intensive Finnish sauna (80C, 1 hr, 2x/day for 7 days) showed a 4-fold rise in prolactin; 5 of 7 developed transient amenorrhea. Demonstrates that extreme heat protocols can suppress the female reproductive axis.

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2018 · review · 5 of 12

Heat stress on reproductive function and fertility in mammals

Roth Z · Animal Reproduction Science

In females, heat stress adversely impacts oogenesis, oocyte maturation, fertilization, and implantation rate. Effects include reduced mitochondrial function, increased ROS, and altered granulosa cell steroidogenesis.

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2012 · analytical · 6 of 12

Human excretion of bisphenol A: Blood, urine, and sweat (BUS) study

Genuis SJ, Beesoon S, Birkholz D, Lobo RA · Journal of Environmental and Public Health

BPA detected in sweat of 80% of participants, including some with no detectable BPA in serum or urine. Sweat may be a meaningful elimination pathway for this reproductive toxicant. Supports IR sauna for detoxification.

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2001 · interventional · 7 of 12

Improvement of semen quality by nocturnal scrotal cooling and moderate behavioral change

Jung A, Schuppe HC · Human Reproduction

Nocturnal scrotal cooling decreased scrotal temperature by ~1C and produced highly significant increases in sperm concentration and total sperm count. One of the best-supported non-pharmacological male fertility interventions.

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2021 · crossover · 8 of 12

Endocrine effects of repeated hot thermal stress and cold water immersion in young adult men

Pilch W, Pokora I, Szyguła Z, et al. · International Journal of Occupational Medicine and Environmental Health

Repeated cold water immersion decreased serum testosterone and estradiol in young men with no change in LH or DHEAS. Acute cold transiently reduces testosterone — important consideration for male fertility.

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2021 · animal interventional · 9 of 12

Brown adipose tissue activation by cold treatment ameliorates polycystic ovary syndrome in rat

Yuan X, Wei G, You Y, et al. · Proceedings of the National Academy of Sciences

20 days of cold exposure (4C) reversed PCOS: restored estrous cycles, reduced testosterone and LH, reduced cystic follicles, and improved insulin sensitivity. BAT activation mediated the effect through improved glucose metabolism.

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2021 · review · 10 of 12

Temperature regulation in women: Effects of the menstrual cycle

Baker FC, Siboza F, Fuller A · Temperature

Core body temperature is 0.3-0.7C higher in the luteal phase than follicular. The thermoregulatory set-point is raised by progesterone. The luteal phase is more vulnerable to heat stress due to this elevated baseline.

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2025 · RCT · 11 of 12

Whole-body cryostimulation exposures effectively alleviate menstrual-related pain and associated sleep disturbances in young women

Bouzigon R, et al. · Cryobiology

Whole-body cryotherapy (-110C, 3 min sessions) significantly reduced menstrual pain and improved sleep quality. Supports cold therapy for dysmenorrhea management.

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2002 · review · 12 of 12

The role of heat shock proteins in reproduction

Neuer A, Spandorfer SD, Giraldo P, et al. · Human Reproduction Update

HSPs are expressed during oogenesis, spermatogenesis, and early pregnancy. They are upregulated by thermal stress and protect gametes at mild doses, but excessive HSP production and anti-HSP antibodies are associated with implantation failure.

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A paper's presence documents the evidence reviewed; it does not mean Filia endorses every intervention or conclusion.