3 papers reviewed
PMS & PMDD — Evidence-Based Management
2009 · systematic review · 1 of 3
Herbs, vitamins and minerals in the treatment of premenstrual syndrome: a systematic review
Whelan AM et al. · Canadian Journal of Clinical Pharmacology
Of the many supplements marketed for PMS, only calcium had good-quality evidence supporting use. Calcium 1,200 mg/day showed roughly 48% reduction in total PMS symptoms and 30% reduction in PMDD symptoms.
Read the paper ↗1999 · systematic review / meta-analysis · 2 of 3
Vitamin B6 in the treatment of premenstrual syndrome: a systematic review
Wyatt KM et al. · BMJ
Across 9 trials and 940 women, vitamin B6 up to 100 mg/day improved overall premenstrual symptoms (OR 2.32) and depressive symptoms (OR 1.69), though most included trials were low quality. Note the app defaults to 10-25 mg daily for neuropathy safety — PMS trial dosing is higher but typically luteal-phase only, which materially reduces cumulative exposure compared with year-round daily use.
Read the paper ↗2020 · pilot RCT · 3 of 3
A pilot randomized treatment-controlled trial comparing vitamin B6 with broad-spectrum micronutrients for premenstrual syndrome
— · Journal of Alternative and Complementary Medicine
Compared isolated B6 against broad-spectrum micronutrients, informing whether single-nutrient or multi-nutrient approaches perform better for premenstrual symptoms.
Read the paper ↗A paper's presence documents the evidence reviewed; it does not mean Filia endorses every intervention or conclusion.