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Supplements: what the evidence says

Supplements: what the evidence says · Step 2 of 7

Vitex (chasteberry)

For luteal support & prolactin

BModerate evidence

The most-studied herbal supplement for cycle health. A double-blind 1993 RCT showed 20mg/day for 3 months normalized shortened luteal phases and corrected progesterone deficits in women with latent hyperprolactinemia.

A systematic review of 12 RCTs found Vitex superior to placebo for PMS (7 of 8 trials positive) and comparable to bromocriptine for mild prolactin elevation, with fewer side effects.

Caution: May interact with dopamine-related medications. Not recommended during pregnancy or with IVF medications. Best used under provider guidance when luteal phase deficiency is confirmed by charting.

Dose
20 mg/day standardized extract
Duration
3 months minimum
Best for
Luteal phase deficiency, mild hyperprolactinemia, PMS